(Adnkronos)-”the kind of reprogramming obtained for the first time since research team-added Dr. Margaret Maioli – it’s a direct cell reprogramming.
Instead of sending a non-adult stem cell back in time until it becomes almost embryonic and then from there to get a differentiation has managed to turn this mature cell a direct route, or to direct it towards more cell fates, in this case, cardiac, and skeletal muscle, neuronal, as if you are already a departed embryonic “. Hence the parallel with the idea of a ‘ time machine ‘. The other new ‘ absolute and was to avoid the use of viral vectors and genetic engineering techniques. “Reac technology-has, in fact, stressed Rinaldi-and in particular the specific protocols developed specifically for this study lead safely, without risk of cancer, changes in cell fate related to the modulation of gene expression and molecular signals network and physicists that control cellular homeostasis”. “It’s remarkable how the reprogrammed human fibroblasts by research team showed the same efficiency of transformation which would be starting with embryonic stem cells, as this research group had already shown” continued Rinaldi, concluding that “the percentages obtained differentiation with Reac technology have vastly superior to any other previous technique, producing cell lines immediately usable and safe. In short, he concluded, “our study used therapeutically immediately makes the reprogramming of fibroblasts, representing the evolution of the work begun by the Nobel Prize for medicine Shinya Yamanaka”.
Image courtesy of mariopiperni